All Things Audio Stem Separation Stem separation is the process of taking a song and splitting it up into unique parts. The basic version of this is : Instrumental Vocals The more complex version of this is : Bass Drums Vocals Other It used to be that you needed to use iZotope RX for this. RX is still great, but there are open source solutions that are pretty darn good.  May I recommend : Ultimate Vocal Remover Website here / Github here Here's a great recipe to use. You need to download some of these models within the app's settings first.  Also, even though it says GPU conversion only works for NVIDIA, it makes a huge difference on Apple Silicone if you have it checked. woooooooo